BDBM50502505 CHEMBL4439573

SMILES Fc1cc2nc(-c3cncnc3C(F)(F)F)n(C3CC3)c2cc1F

InChI Key InChIKey=VNILRKBSTICRTL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50502505   

TargetCytochrome P450 11B2, mitochondrial(Human)
Selenity Therapeutics

Curated by ChEMBL
LigandPNGBDBM50502505(CHEMBL4439573)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant CYP11B2 using deoxycorticosterone as substrate incubated for 90 mins by cell-based HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Selenity Therapeutics

Curated by ChEMBL
LigandPNGBDBM50502505(CHEMBL4439573)
Affinity DataIC50: 4.77E+3nMAssay Description:Inhibition of human recombinant CYP11B1 using deoxycortisol as substrate incubated for 60 mins by cell-based HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Selenity Therapeutics

Curated by ChEMBL
LigandPNGBDBM50502505(CHEMBL4439573)
Affinity DataIC50: 6.45E+3nMAssay Description:Inhibition of CYP19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed