BDBM50502549 CHEMBL4453315

SMILES O=C1CCc2ccccc2N1CCCCN1CCN(CC1)c1ccccn1

InChI Key InChIKey=FPVLBAXLMUJERT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50502549   

TargetSigma intracellular receptor 2(Rat)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50502549(CHEMBL4453315)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50502549(CHEMBL4453315)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50502549(CHEMBL4453315)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed