BDBM50503146 CHEMBL4447266

SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Br)cc1)c1c(-c2ccccc2)c2cc(Br)ccc2[nH]c1=O

InChI Key InChIKey=VXQKNIKPZQKQEY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503146   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503146(CHEMBL4447266)
Affinity DataIC50: 7.80E+4nMAssay Description:Negative allosteric modulation of GluN2B receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503146(CHEMBL4447266)
Affinity DataIC50: 1.90E+4nMAssay Description:Negative allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503146(CHEMBL4447266)
Affinity DataIC50: 5.40E+3nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503146(CHEMBL4447266)
Affinity DataIC50: 2.70E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed