BDBM50503490 CHEMBL4549344

SMILES COc1ccc(c(F)c1)-c1cc(nc2cc(COc3ccc(nc3)C(F)(F)F)nn12)C(N)=O

InChI Key InChIKey=JOSLFAPFDFTKSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503490   

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503490(CHEMBL4549344)
Affinity DataIC50: 347nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503490(CHEMBL4549344)
Affinity DataIC50: 347nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed