BDBM50503684 CHEMBL4458350

SMILES [H][C@@]12CN3CC[C@@]1([H])c1cc(CC\C=C/CCCC3)c[n+](CCCC\C=C/CC2)c1

InChI Key InChIKey=KZDYUCMVPIMNIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503684   

TargetProteasome subunit beta type-8(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 20s immunoproteasome LMP7 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 20s immunoproteasome LMP2 in human erythrocytes using Ac-Pro-Ala-Leu-MCA as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta5 chymotrypsin-like activity in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed