BDBM50503842 CHEMBL4439673

SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)NCC(C)(C)N)cc2C)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=QJVWEELRAXACME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503842   

TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50503842(CHEMBL4439673)
Affinity DataIC50: 54nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50503842(CHEMBL4439673)
Affinity DataIC50: 322nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed