BDBM50503977 CHEMBL4465902

SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Nc1ccc(OCCCCCn2cc(CNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)nn2)cc1

InChI Key InChIKey=DQGQXFRCIYCGOE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50503977   

TargetHistone deacetylase 6(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human N-terminal tagged human HDAC6 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC5 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC9 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC7 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC1 expressed in HEK293T/17 using Ac-Gly-Ala-[Ac-Lys]-AMC as substrate preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC11 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC4 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Institute of Biotechnology of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50503977(CHEMBL4465902)
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal tagged human HDAC8 expressed in HEK293T/17 using Boc-[TFA-Lys]-AMC as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed