BDBM50504012 CHEMBL4441996

SMILES [H][C@@]12C[C@@]1(CCOC2)c1cc(nc(n1)-c1ccc(NC(=O)CNC)cc1)C(C)(C)S(C)(=O)=O

InChI Key InChIKey=QVXOKNZQEPYXBI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50504012   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50504012(CHEMBL4441996)Copy SMILESCopy InChI

Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by H...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50504012(CHEMBL4441996)Copy SMILESCopy InChI

Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by H...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL