BDBM50504292 CHEMBL4589224

SMILES NS(=O)(=O)c1ccc(C\N=C\c2cc(Br)ccc2OCc2cn(CCCOc3ccc4ccc(=O)oc4c3)nn2)cc1

InChI Key InChIKey=CWNSIECFTJQYPQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50504292   

TargetCarbonic anhydrase 9(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50504292(CHEMBL4589224)
Affinity DataKi:  160nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 10 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50504292(CHEMBL4589224)
Affinity DataKi:  791nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 10 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50504292(CHEMBL4589224)
Affinity DataKi:  919nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 10 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50504292(CHEMBL4589224)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 10 mins prior to testing measured for 5 to 10 secs by phenol red-based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed