BDBM50504677 CHEMBL4459946

SMILES CN1CCN(CC1)C(=O)COc1ccc(cc1)C(=O)C=Cc1ccccc1C(F)(F)F

InChI Key InChIKey=LEXYWKGISNTGKV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50504677   

TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50504677(CHEMBL4459946)
Affinity DataEC50:  630nMAssay Description:Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed