BDBM50504708 CHEMBL4446546

SMILES CC\C=C/C(=O)Nc1cc(Nc2nc3CCSCc3c(n2)-c2cn(C)c3ccccc23)c(OC)cc1N(C)CCN(C)C

InChI Key InChIKey=HONXHUSIBHCYQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50504708   

TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50504708(CHEMBL4446546)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using biotin as substrate in presence of ATP by mobility shift assay based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50504708(CHEMBL4446546)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wildtype EGFR (unknown origin) using biotin as substrate in presence of ATP by mobility shift assay based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed