BDBM50504709 CHEMBL4475770

SMILES [#6]-[#8]-c1cc(-[#7](-[#6])-[#6]-[#6]-[#7](-[#6])-[#6])c(-[#7]-[#6](=O)\[#6]=[#6](/[#6])-[#6])cc1-[#7]-c1nc2-[#6]-[#6]S(=O)(=O)[#6]-c2c(n1)-c1cn(-[#6])c2ccc(F)cc12

InChI Key InChIKey=QJATWFNDOXFARM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50504709   

TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50504709(CHEMBL4475770)
Affinity DataIC50: 201nMAssay Description:Inhibition of wildtype EGFR (unknown origin) using biotin as substrate in presence of ATP by mobility shift assay based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50504709(CHEMBL4475770)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using biotin as substrate in presence of ATP by mobility shift assay based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed