BDBM50504753 CHEMBL4585562

SMILES Nc1nc(NC(=O)Nc2ccccc2)nn1-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=MDFYLPAPFMHRAH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50504753   

TargetCarbonic anhydrase 12(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504753(CHEMBL4585562)
Affinity DataKi:  8.10nMAssay Description:Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504753(CHEMBL4585562)
Affinity DataKi:  8.20nMAssay Description:Inhibition of recombinant human carbonic anhydrase-9 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504753(CHEMBL4585562)
Affinity DataKi:  9.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50504753(CHEMBL4585562)
Affinity DataKi:  442nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 incubated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed