BDBM50504993 CHEMBL4465098

SMILES COc1ccc(cc1CO[C@@H]1[C@H]([C@@H](N([C@@H]1c1ccccc1)C(=O)C1CCCCC1)C(O)=O)C(C)(C)C)C(F)(F)F

InChI Key InChIKey=WREYIHKXCVYUNM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50504993   

LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50:  1.13E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50:  1.13E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50:  1.32E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50504993(CHEMBL4465098)
Affinity DataEC50: >2.00E+4nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed