BDBM50505164 CHEMBL4440907

SMILES Oc1cc(C(N(CCCl)CCCl)c2ccsc2)c(O)c2C(=O)c3ccccc3C(=O)c12

InChI Key InChIKey=IJBUOJARHXEQRU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50505164   

TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50505164(CHEMBL4440907)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of topoisomerase 2 in human HepG2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50505164(CHEMBL4440907)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of topoisomerase 2 in human HeLa cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50505164(CHEMBL4440907)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of topoisomerase 2 in human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50505164(CHEMBL4440907)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of topoisomerase 2 in human MDA-MB-231 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50505164(CHEMBL4440907)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of topoisomerase 2 in human MCF7 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50505164(CHEMBL4440907)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of topoisomerase 2 in human CNE1 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed