BDBM50505900 CHEMBL4449421

SMILES CNC(=O)c1ccc(C)c(NC(=O)c2ccc(s2)-c2ccccc2Cl)c1

InChI Key InChIKey=ZRUOULNVAKXPOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505900   

TargetMitogen-activated protein kinase 14(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505900(CHEMBL4449421)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505900(CHEMBL4449421)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed