BDBM50506265 CHEMBL4469904

SMILES COc1cc(cc2nc(NC(=O)c3ccccn3)n(CCCNC(=O)OCc3ccccc3)c12)C(N)=O

InChI Key InChIKey=NQLBMNVGWZHBCC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506265   

TargetInterferon regulatory factor 3(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506265(CHEMBL4469904)
Affinity DataEC50: >1.00E+5nMAssay Description:Induction of IRF3 pathway in STING knockout human THP1 cells measured after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506265(CHEMBL4469904)
Affinity DataEC50:  8.28E+3nMAssay Description:Agonist activity at STING in human THP1 cells assessed as stimulation of IRF3 pathway measured after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed