BDBM50506444 CHEMBL4475726

SMILES COc1cc(NC(=O)c2ccc(C)c(c2)C#Cc2cncc3ccccc23)cc(OC)c1

InChI Key InChIKey=UHLRTBUQNQGWLS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50506444   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506444(CHEMBL4475726)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant CSF1R (unknown origin) using poly (Glu, Tyr)4:1 as substrate measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506444(CHEMBL4475726)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged FGFR4 (442 to 755 residues) expressed in baculovirus infected Sf21 insect cells using poly (Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506444(CHEMBL4475726)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged FGFR3 (447 to 761 residues) expressed in baculovirus infected Sf21 insect cells using poly (Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506444(CHEMBL4475726)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR1 (456 to 765 residues) expressed in baculovirus infected Sf21 insect cells using poly (Glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50506444(CHEMBL4475726)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged FGFR2 (456 to 770 residues) expressed in baculovirus infected Sf21 insect cells using poly (Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed