BDBM50506547 C-533,536-02::CP-533536-02::Evatanepag sodium

SMILES CC(C)(C)c1ccc(CN(Cc2cccc(OCC([O-])=O)c2)S(=O)(=O)c2cccnc2)cc1

InChI Key InChIKey=WOHRHWDYFNWPNG-UHFFFAOYSA-M

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506547   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Ube Industries

Curated by ChEMBL
LigandPNGBDBM50506547(C-533,536-02 | CP-533536-02 | Evatanepag sodium)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Ube Industries

Curated by ChEMBL
LigandPNGBDBM50506547(C-533,536-02 | CP-533536-02 | Evatanepag sodium)
Affinity DataEC50:  17nMAssay Description:Agonist activity at recombinant human EP2 receptor expressed in HEK293 cells assessed as induction of cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed