BDBM50506700 CHEMBL4439395

SMILES O=C(Cc1ccc(cc1)-c1ccccc1)Nc1cc([nH]n1)C1CCC1

InChI Key InChIKey=DTNFOGMAASDEQI-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50506700   

TargetHigh affinity nerve growth factor receptor(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 12(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPK14 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK5/p35 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK2/CyclinE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 911nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eppley Institute For Research In Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed