BDBM50506848 CHEMBL4556728

SMILES Nc1cc(ccc1NC(=O)Nc1ccc(cc1)S(=O)(=O)Oc1cccc(CC(=O)Oc2cccc(CC(O)=O)c2)c1)C(F)(F)F

InChI Key InChIKey=VUDDWKQGYZRKCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506848   

TargetGenome polyprotein(Dengue virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506848(CHEMBL4556728)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of DENV3 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506848(CHEMBL4556728)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed