BDBM50506888 CHEMBL4541580

SMILES COc1cc2CCN(Cc3cccc(COc4ccc5ccc(=O)oc5c4)c3)Cc2cc1OC

InChI Key InChIKey=QOKZZPBLVVZFTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506888   

TargetATP-dependent translocase ABCB1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50506888(CHEMBL4541580)
Affinity DataIC50: 770nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as reduction in calcein-AM efflux preincubated for 30 mins followed by calcein-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50506888(CHEMBL4541580)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as reduction in calcein-AM efflux preincubated for 30 mins followed by calcein-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed