BDBM50507192 CHEMBL4441769

SMILES [H][C@@]1(COC(=O)N1c1ccnc(NC2(CC2)c2cn(cn2)-c2ccccc2C(F)(F)F)n1)[C@H](C)F

InChI Key InChIKey=ZWSHGRQGEGGLEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50507192   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507192(CHEMBL4441769)
Affinity DataIC50: 112nMAssay Description:Inhibition of IDH1 (unknown origin) R132H mutant using alpha-KG as substrate after 60 mins in presence of NADPH by resazurin dye-based fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed