BDBM50507551 CHEMBL4587222

SMILES CCN1CCN(CCCOc2cc3nccc(Oc4c(F)cc(NC(=O)NN5C(SCC5=O)c5c(F)cccc5F)cc4F)c3cc2OC)CC1

InChI Key InChIKey=GZVQZLVAKXRTHU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50507551   

TargetTyrosine-protein kinase receptor UFO(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 53nMAssay Description:Inhibition of AXL (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 15nMAssay Description:Inhibition of c-Met (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 64nMAssay Description:Inhibition of c-Kit (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 850nMAssay Description:Inhibition of KDR (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 240nMAssay Description:Inhibition of c-Src (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 520nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of IGF-1R (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER-2 (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Ron (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed