BDBM50507697 CHEMBL4564622

SMILES ONC(=O)c1ccc(Cn2c3ccccc3c(=O)n(CCc3cccc(c3)C(F)(F)F)c2=O)cc1

InChI Key InChIKey=IVOKPEDWUKQUED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507697   

TargetHistone deacetylase 6(Human)
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507697(CHEMBL4564622)
Affinity DataIC50: 24nMAssay Description:Inhibition of human full-length recombinant HDAC6 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507697(CHEMBL4564622)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of human full-length recombinant HDAC8 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKAcKAc as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507697(CHEMBL4564622)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of human full-length recombinant HDAC1 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKKAc as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed