BDBM50508247 CHEMBL4467855

SMILES COc1ccc2c(cn(CCCn3ccnc3)c2c1)C1=C(C(=O)NC1=O)c1nn(C)c2ncccc12

InChI Key InChIKey=OBHZQTFINGNSFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508247   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50508247(CHEMBL4467855)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human N-terminal GST-fused IDH1 R132H mutant expressed in Escherichia coli using alpha-ketoglutarate as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed