BDBM50508369 CHEMBL4578409

SMILES Clc1cc(CN2CCN(CC2)C(=O)c2ccc(o2)-c2ccccc2Cl)ccc1OC1CCNCC1

InChI Key InChIKey=PAIVDRXUSLYHKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508369   

TargetUrotensin-2 receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50508369(CHEMBL4578409)
Affinity DataIC50: 33nMAssay Description:Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50508369(CHEMBL4578409)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human UT2 receptor expressed in HEK293-aeq cells assessed as inhibition of U2-induced intracellular calcium mobilization prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed