BDBM50508651 CHEMBL4435000

SMILES Cn1c(c(C2CCCCC2)c2ccc(cc12)C(=O)NS(=O)(=O)C1CC1)-c1ccc(nc1)C#N

InChI Key InChIKey=AZUZRDXBBXSVDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508651   

TargetSodium channel protein type 9 subunit alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50508651(CHEMBL4435000)
Affinity DataIC50: 123nMAssay Description:Inhibition of human Nav1.7 at -60 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50508651(CHEMBL4435000)
Affinity DataIC50: 366nMAssay Description:Inhibition of human Nav1.7 at -60 mV holding potential by cell-based manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed