BDBM50508760 CHEMBL4435423

SMILES CN1CC(n2c(Cn3ncc(C)n3)nc3cnc4ccc(cc4c23)C#N)C(F)(F)C1

InChI Key InChIKey=SXIUZTAWZDYLBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508760   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508760(CHEMBL4435423)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S mutant (unknown origin) expressed in baculovirus expression system using fluorescein-labeled LRRKtide as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508760(CHEMBL4435423)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant wild-type GST-tagged LRRK2 (unknown origin) expressed in baculovirus expression system using fluorescein-labeled LRRKtide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed