BDBM50508933 CHEMBL4461511

SMILES [H][C@@]12CC=C(C)[C@@]([H])(C1)[C@]([H])(NC2(C)C)c1ccnc2ccccc12

InChI Key InChIKey=HQDLJJQZMYAAPU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50508933   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508933(CHEMBL4461511)
Affinity DataIC50: 960nMAssay Description:Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508933(CHEMBL4461511)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
American University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50508933(CHEMBL4461511)
Affinity DataIC50: 4.53E+4nMAssay Description:Antagonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed