BDBM50508990 CHEMBL4472294

SMILES C[C@@H](c1ccccc1)n1nnc2cnc3ccc(cc3c12)-c1cnc2[nH]ccc2c1

InChI Key InChIKey=LCQSLPADLYHOIN-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50508990   

TargetSerine/threonine-protein kinase LATS2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50508990(CHEMBL4472294)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to wild-type human partial length LATS2 (Q641 to V1088 residues) expressed in mammalian expression system assessed as dissociation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50508990(CHEMBL4472294)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MST2 (2 to end residues) assessed as residual activity using myelin basic protein as substrate measured after 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50508990(CHEMBL4472294)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full-length human MST1 assessed as residual activity using KKSRGDYMTMQIG as substrate measured after 40 mins in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase LATS1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50508990(CHEMBL4472294)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to recombinant human LATS1 (Q678 to V1130 residues) expressed in bacterial expression system assessed as dissociation constant by Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed