BDBM50509618 CHEMBL4463663

SMILES Nc1cc(F)c(cc1C(=O)Nc1cc(F)c(F)c(F)c1)S(=O)(=O)N1CCC(O)CC1

InChI Key InChIKey=VPVGGXRVWGBGDZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50509618   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509618(CHEMBL4463663)
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of human ERG expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509618(CHEMBL4463663)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human ERG by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509618(CHEMBL4463663)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human CYP2C9 using tolubutamide as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509618(CHEMBL4463663)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of human CYP2C19 using S-mephenytoin as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509618(CHEMBL4463663)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of human CYP3A4 using sorafenib as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509618(CHEMBL4463663)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of human CYP2D6 using dextromethorphan as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509618(CHEMBL4463663)
Affinity DataIC50: 8.11E+4nMAssay Description:Inhibition of human CYP1A2 using phenacetin as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed