BDBM50509870 CHEMBL4461011

SMILES CC(C)(C)CNc1c(cnn2cc(cc12)-c1ccccc1)C(N)=O

InChI Key InChIKey=XTJVPAIZQKWZNS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50509870   

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509870(CHEMBL4461011)
Affinity DataIC50: 8nMAssay Description:Inhibition of GST-tagged JAK3 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509870(CHEMBL4461011)
Affinity DataIC50: 33nMAssay Description:Inhibition of GST-tagged JAK1 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509870(CHEMBL4461011)
Affinity DataIC50: 70nMAssay Description:Inhibition of Hs-tagged TYK2 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509870(CHEMBL4461011)
Affinity DataIC50: 110nMAssay Description:Inhibition of GST-tagged JAK2 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed