BDBM50509881 CHEMBL4589996

SMILES CC(=O)c1cccc2c(C)c(sc12)C(=O)Nc1ccc2ccccc2n1

InChI Key InChIKey=NZTWZRXIEOVSMN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509881   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Asubio Pharma

Curated by ChEMBL

LigandBDBM50509881(CHEMBL4589996)Copy SMILESCopy InChI

Affinity DataIC50: 7.60nMAssay Description:Inhibition of human MOLT4 cell-derived PDE10A using [3H]cAMP as substrate measured after 2 hrs in presence of rolipram/milrinone by topcount methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
Copy BDB DOIPubMed
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TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Asubio Pharma

Curated by ChEMBL

LigandBDBM50509881(CHEMBL4589996)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MOLT4 cell-derived PDE7 using [3H]cAMP as substrate measured after 2 hrs in presence of rolipram/milrinone by topcount methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL