BDBM50509887 CHEMBL4529098

SMILES Cc1c(sc2c(cccc12)-c1ccncc1)C(=O)Nc1ccc2ccccc2n1

InChI Key InChIKey=NLHBWKNEYCCCRY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50509887   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Asubio Pharma

Curated by ChEMBL

LigandBDBM50509887(CHEMBL4529098)Copy SMILESCopy InChI

Affinity DataIC50: 4.70nMAssay Description:Inhibition of human MOLT4 cell-derived PDE10A using [3H]cAMP as substrate measured after 2 hrs in presence of rolipram/milrinone by topcount methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
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