BDBM50510035 CHEMBL4528810

SMILES Cc1nn(c(C)c1-c1cccc(F)c1)-c1ccc2CNCc2c1

InChI Key InChIKey=AAQNJVGFIFCTMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510035   

TargetAcid-sensing ion channel 2(Mouse)
Promidis

Curated by ChEMBL
LigandPNGBDBM50510035(CHEMBL4528810)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Mouse)
Promidis

Curated by ChEMBL
LigandPNGBDBM50510035(CHEMBL4528810)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcid-sensing ion channel 2(Mouse)
Promidis

Curated by ChEMBL
LigandPNGBDBM50510035(CHEMBL4528810)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of pH 5.5-stimulated mouse ASIC2a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed