BDBM50510205 CHEMBL4461441

SMILES COc1cc(cc(OC)c1OC)-c1nc(NCc2cccc(\C=C\C(=O)NO)c2)cc2c3ccccc3[nH]c12

InChI Key InChIKey=IVSCKYBGQGPVDS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50510205   

TargetHistone deacetylase 1(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50510205(CHEMBL4461441)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50510205(CHEMBL4461441)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50510205(CHEMBL4461441)
Affinity DataIC50: 146nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50510205(CHEMBL4461441)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC8 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins and measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed