BDBM50510248 CHEMBL4575083

SMILES COc1ccc(cc1)-c1ccc2ncc(-c3nnc(C)o3)c(NCCN3CCOCC3)c2c1

InChI Key InChIKey=POQMMYBPDFBLGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510248   

TargetDNA topoisomerase 1(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50510248(CHEMBL4575083)
Affinity DataIC50: 1.00E+4nMAssay Description:Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed