BDBM50510512 CHEMBL4451013

SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)n1cc2c(n1)c1ccccc1oc2=O

InChI Key InChIKey=QKAAKWXFXXSWER-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50510512   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
School of Traditional Chinese Pharmacy

Curated by ChEMBL
LigandPNGBDBM50510512(CHEMBL4451013)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
School of Traditional Chinese Pharmacy

Curated by ChEMBL
LigandPNGBDBM50510512(CHEMBL4451013)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
School of Traditional Chinese Pharmacy

Curated by ChEMBL
LigandPNGBDBM50510512(CHEMBL4451013)
Affinity DataIC50: 9.49E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
School of Traditional Chinese Pharmacy

Curated by ChEMBL
LigandPNGBDBM50510512(CHEMBL4451013)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed