BDBM50510536 CHEMBL4456976

SMILES CC(C)c1ccc(CSc2nc3[nH]c(C)cc(=O)n3n2)cc1

InChI Key InChIKey=YIGHPAMCXNISKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510536   

TargetEpidermal growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50510536(CHEMBL4456976)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R/T790M mutant expressed in baculovirus expression system reduction in phosphorylation using tyro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50510536(CHEMBL4456976)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R mutant expressed in baculovirus expression system reduction in phosphorylation using tyrosine 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50510536(CHEMBL4456976)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant His-tagged cMET expressed in baculovirus expression system reduction in phosphorylation using tyrosine 6 peptide as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed