BDBM50510665 CHEMBL4439903

SMILES CC[C@](CO)(c1ccc(Cl)cc1)n1ccc2c(NS(C)(=O)=O)cccc12

InChI Key InChIKey=RKFFHZQKHIMLAH-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50510665   

TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 22nMAssay Description:Binding affinity to mineralocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 54nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 125nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by gel filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at progesterone receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed