BDBM50510775 CHEMBL4445405

SMILES C[C@]1(C[C@H](SC(N)=N1)C(F)(F)F)c1cc(NC(=O)c2ccc(OCF)cn2)ccc1F

InChI Key InChIKey=SNMHOUWVJNSJDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510775   

TargetBeta-secretase 2(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50510775(CHEMBL4445405)
Affinity DataIC50: 1nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50510775(CHEMBL4445405)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed