BDBM50510816 CHEMBL4475802

SMILES CC(F)(F)[C@@H]1C[C@](C)(N=C(N)S1)c1cc(NC(=O)c2ccc(OCF)cn2)ccc1F

InChI Key InChIKey=RDTPYVBRIVZCGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510816   

TargetBeta-secretase 2(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50510816(CHEMBL4475802)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50510816(CHEMBL4475802)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed