BDBM50511093 CHEMBL4522871

SMILES CCn1nc(C)cc1C(=O)\N=c1/[nH]c2cc(ccc2n1C[C@@H](O)c1ccccc1)C(N)=O

InChI Key InChIKey=NMXJYHHOVIHSBO-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50511093   

TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human wild type STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataIC50: 14nMAssay Description:Agonist activity to C-terminal domain human STING (139 to 379 residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataEC50:  1.02E+5nMAssay Description:Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of [3H]-cGAMP from human STING CTD (149 to 379 residues) by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataEC50:  1.02E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed