BDBM50511435 CHEMBL4574443

SMILES CNc1cc(Oc2cccc(C)c2C)nc(N)n1

InChI Key InChIKey=OLNMROXLROQDJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511435   

TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50511435(CHEMBL4574443)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed