BDBM50511497 CHEMBL4565522

SMILES CCc1ccc(cc1-c1cc(cc(c1)C(C)(C)C)-c1cnc2cnccn12)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=BWLUTMGITQVVDZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511497   

LigandPNGBDBM50511497(CHEMBL4565522)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length His-tagged Bcr-Abl expressed in baculovirus expression system using tyrosine-2 peptide as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511497(CHEMBL4565522)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged c-Kit cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression system using Ser/Thr 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511497(CHEMBL4565522)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human GST-tagged DDR1 catalytic domain (440 to 876 residues) expressed in baculovirus expression system using Fluorescein-p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50511497(CHEMBL4565522)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged DDR2 cytoplasmic domain (427 to 855 residues) expressed in baculovirus expression system using Fluorescein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed