BDBM50511607 CHEMBL4525209::US12110286, Example 35s

SMILES Cn1c2ccc(Nc3nc(ncc3Cl)N3CC4CCC(C3)C4(F)F)cc2n(CCC(C)(C)O)c1=O

InChI Key InChIKey=MJCXMDHFAYSKJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50511607   

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50511607(CHEMBL4525209 | US12110286, Example 35s)
Affinity DataIC50: 692nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50511607(CHEMBL4525209 | US12110286, Example 35s)
Affinity DataIC50: 710nMAssay Description:Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed