BDBM50512097 CHEMBL4536976

SMILES O=C1CCC(\C=C\c2cccnc2)=NN1

InChI Key InChIKey=HDYDKRBRUUPOGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512097   

TargetProstaglandin G/H synthase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512097(CHEMBL4536976)
Affinity DataIC50: 19nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512097(CHEMBL4536976)
Affinity DataIC50: 750nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed