BDBM50512297 CHEMBL4435158

SMILES CCn1ncc(c1C)-c1nc2c(Oc3csc(c3)C(=O)N3CCOCC3)ncnc2n1C

InChI Key InChIKey=XZICPUZVXHICOX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50512297   

LigandPNGBDBM50512297(CHEMBL4435158)
Affinity DataIC50: 970nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50512297(CHEMBL4435158)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50512297(CHEMBL4435158)
Affinity DataIC50: 68nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed