BDBM50512324 CHEMBL4521278

SMILES COc1cc(ccc1Nc1nc(O[C@H]2CCOC(C)(C)C2)c2cc[nH]c2n1)N1CCN(CC1)C(=O)CO

InChI Key InChIKey=AKEXYGKEZUCKRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512324   

TargetDual specificity protein kinase TTK(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50512324(CHEMBL4521278)
Affinity DataIC50: 16nMAssay Description:Inhibition of TTK autophosphorylation in human CAL51 cells by radioimmuno-precipitation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50512324(CHEMBL4521278)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed